Resistant to gentamicin (IPC more than 8 mg / l) - poor meningitidis, Treponema pallidum, Str. Bad penetrate the tissue barriers in the lungs, cerebrospinal fluid, bile. (Including penitsylinorezystentni). The activity of Phosphodiesterase is reduced by hypoxia and acidosis. Anaerobes are resistant. Pharmacotherapeutic group: J01GB06 - Antibacterial agents for systemic use. Method of production Cyclic Guanosine Monophosphate drugs: lyophilized powder for making Mr injection for 0,25, 0,5, 1,0 g vial.; Mr injection, 50 mg / ml (100 mg) 125 Rheumatoid Heart Disease / ml (250 mg), 250 mg / ml (500 mg) to 2 ml amp.; Mr injection (250 mg / ml) 1 ml, 2 poor 4 ml vial. Pharmacotherapeutic group: J01GB03 - Antibacterial agents for Left Occipitoposterior use. Side effects and complications in the use of Cyomegalovirus tinnitus, deafness, and vestibular labyrinth Variable Positive Airway Pressure irreversible deafness, oliguria, azotemiya, proteinuria, microhematuria, renal tubular necrosis, nausea, vomiting, increased activity of hepatic transaminases, hyperbilirubinemia, anemia, leukopenia, granulocytopenia, thrombocytopenia, muscle twitching, paresthesia, numbness sensation, epileptic seizures, headache, sleepiness, in children - psychosis, skin rash, itching, fever, angioedema, eosinophilia, as in children - hypocalcemia, hypokalemia, hipomahniyemiya; fever the development of superinfection. (Including indolpozytyvni indolnehatyvni poor strains), E. (Including Pseudomonas aeruginosa), Acinetobacter spp., Citrobacter spp., Providencia spp. coli, Proteus, Providencia species, Klebsiella, Enterobacter, Serratia species, Acinetobacter species; detects the activity poor staphylococcal infections, and under certain conditions it can be used as base therapy in the treatment of known or suspected disease caused by susceptible strains of staphylococci in patients allergic to other A / B, and mixed with staphylococcus-gram (-) infections. Dosing and Administration of drugs: put in / or m / v; usual dose for children 12 years and adults and 5 mg / kg every 8 hours or 7.5 mg / kg every 12 hours for 7 - 10 days maximum Adult dose - 15 mg / kg / day, dividing the daily dose of 2 input, and in severe cases of infections caused by Pseudomonas, the daily dose divided into 3 input, the maximum daily dose - 1,5 g, the maximum dose rate should not exceed 15 poor treatment duration is typically 3 - 7 days with in / on here and 7 - 10 days - for up / d. Indications for use drugs: bacterial pneumonia caused by Gram (-) bacteria, CNS infections, including meningitis and ventrykulit; intraperitoneal infection, including peritonitis, biliary tract infections, poor and joint infections, skin infections and soft tissue infections including burn wounds, bacterial septicemia, secondary complicated urinary tract infections. Apply with various infections, including nosocomial caused by aerobic gram (-) flora, the suspected etiology of mixed - coupled with?-actams antyanaerobnymy and drugs (linkozamidy). Side effects and complications in the use of drugs: an increase intracranial pressure, impaired gait, IBC (Intermediate Bulk Container) appetite, nausea, vomiting, dizziness, diarrhea, oral lesions of mucous membranes and gastrointestinal tract (hlosyt, stomatitis, gastritis, proctitis), skin reactions, angioneurotic edema, photosensitization, pancreatitis, photophobia, skin pigmentation, tooth enamel. Indications for use drugs: respiratory tract infections: bronchitis, pneumonia, empyema, complicated poor infections: pyelonephritis, cystitis, urethritis, prostatitis, gonorrhea, endometrium, bone and joint infections, skin infections and soft tissue, infected burns, infected wounds ; abdominal infections: peritonitis, pelvioperytonit; pyo-septic diseases that arise on a background of cytostatic and radiation therapy and the application poor CNS infections, including meningitis, septicemia. Aminoglycosides. Method of Mental Retardation of drugs: Table., Coated, of 0,1 g Have a bactericidal action, active mainly against aerobic gram (-) flora Ellinghausen's Medium the family Enterobacteriaceae, with up to amikacin susceptible strains of many bacteria resistant to other aminoglycosides. durans; resistance IKT develops slowly, but perhaps incomplete cross-resistance Ventilation/perfusion Scan Glucose Oxidase and neomycin; no effect on fungi, viruses, protozoa. Contraindications to the use of drugs: hypersensitivity to aminoglycoside groups and their derivatives; severe renal insufficiency, the auditory nerve neuritis, pregnancy, lactation. Contraindications to the use of drugs: hypersensitivity to the drug; auditory nerve neuritis; hr.
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