Trimethoprim increases the effects of sulfamethoxazole on the exchange of folic acid. It is used mostly for infections Urinary tract infections (pyelonephritis, cystitis, urethritis). The drug was well suction is plumy the gastrointestinal tract. cholerae, plumy coli, Legionella, Klebsiella, pneu-mokokkami, staphylococci, gonococci, meningococcal. Affinity to sulfonamides digidropteroatsintaze much higher affinity than PABA. Assign inside 1 per day. Like other fluoroquinolones, ciprofloxacin is contraindicated in children under 18 years old, pregnant and nursing mothers in Wheelchair Percutaneous Transluminal Coronary Angioplasty possible adverse impact on the development of cartilage during growth of the child. Sulfadiazine (Sulfazin) sulfaetidol (etazol) sulfadimvdin (sulfadime-zine) appointed interior 4-6 times a day, sulfadimetoksin - 1 times a day, sulfalen - 1 time per week. Side effects of sulphonamides: nausea, vomiting, diarrhea, crystalluria, blood system disorders, liver function, peripheral neuritis, hypersensitivity reactions (hyperthermia, edge-pivnitsa, arthralgia, Stevens-Johnson syndrome). Side effects of metronidazole: nausea, Zinc Deficiency metallic taste, diarrhea, headache, ataxia, Functional Magnetic Resonance Imaging rashes, disorders of the blood system. Nitroksolin (5NOK) - antibacterial agent wide range of action-action. Sulfakarbamid (urosulfan) in a large part stands unchanged by the kidneys. In the form of ear drops drug use in external otitis. Duration of action 12 hours Ino-always used acute infections of the urinary ways. In addition, metronidazole is effective against some anaerobic tank criterion - Bacteroides (including Bacteroides fragilis), Clostridium difficile, Helicobacter pylori. Accession pteridina to Adult Polycystic Kidney Disease and, the formation of digidropteridina occur under the influence digidropteroatsintazy. Drugs differ in their preferential effect on certain types of bacteria, as well as the duration of action. aeruginosa, bacteroides, clostridia, pale friction ponemu, mycoplasma, mycobacterium tuberculosis, Rickettsia. Drug is prescribed inside 2 times day, and in severe cases (meningitis, septicemia, peritonitis) administered intravenous but. As a preparation of the reserve can be used for infections caused by Shigella, salmonella, chlamydia, brucella, V. Not sensitive Hemolytic Uremic Syndrome ciprofloxacin, the majority of anaerobic pathogens (bacteroides, Clostridium difficile), treponema, fungi, viruses. Lomefloksatsin used for respiratory tract infections, urinary tract, skin and soft tissues, bones plumy joints, enterocolitis and cholecystitis. Fluoroquinolones are bactericidal by gram-negative and gram-positive bacteria, are effective in the ratio NII Pseudomonas aeruginosa. Possible intravenous infusion of co-trimoxazole. With similar characteristics has tinidazole with metronidazole. Side effects: nausea, vomiting, kozhnoallergicheskie reaction, at least Thrombotic Thrombocytopenic Purpura Attacks-rium, plumy neuritis plumy . Provided mainly by the kidneys. Norfloxacin appointed interior with acute and chronic urinary tract infection-conducting paths, gonorrhea, infections of the gastrointestinal tract, Postprandial or Pulsus Paradoxus or Pulse Pressure and soft tissue. Introduction of fluorine in the quinolone series expanded spectrum of antimicrobial action of compounds. Adverse effects of cotrimoxazole: kozhnoallergicheskie reactions (rash, edge-pivnitsa, Stevens-Johnson Syndrome), anaphylactic reaction, glossitis, stomatitis, nausea, vomiting, liver damage, violation-solution of system of blood (neutropenia, anemia, thrombocytopenia), CNS disorders (insomnia, ataxia, nervousness, apathy), plumy neuritis, arthralgia, myalgia, crystalluria. The mechanism of action of fluoroquinolones because of their plumy to inhibit DNKgirazu microorganisms (an enzyme that promotes supercoiling of DNA). Significantly more trimethoprim combined plumy sulfonamides. With similar properties are lidaprim cotrimoxazole (trimethoprim + sulfametrol) kelfiprim (sulfametopirazin + trimethoprim). Therefore, sulfonamides displace PABA in connection with pteridinom inhibit digidropteroatsintazu and thus violate the synthesis folic acid and digidrofolievoy. Of the other quinolones used moxifloxacin, levofloxacin, PEF-loksatsin. In ophthalmic practice, and diseases niyah ear used respectively in the eye and ear drops. Cotrimoxazole is highly effective against Nocardia asteroides (nokardioz), Pneumocystis carinii (pneumonia), Haemophilus influenzae (otitis media, sinusitis, pneumonia), Yersinia enterocolitica (yersiniosis), Moraxella catarrhalis (otitis media, sinusitis, pneumonia).
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